Strengthening Early TB Detection by Embedding AI into Government-Led Active Case Finding

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Case at a Glance

Impact
12,12,932

12,12,932

beneficiaries screened using AI-enabled chest X-rays

9,804

9,804

TB cases confirmed, including 32% asymptomatic cases

62%

62%

reduction in screening time and cost per beneficiary

About the organisation

The William J. Clinton Foundation (WJCF) is a not-for-profit organisation supporting government-led health systems to reduce disease burden and save lives. WJCF works closely with the Ministry of Health & Family Welfare and state governments across 16 states, focusing on TB, HIV/AIDS, hepatitis, non-communicable diseases, Ayushman Bharat, and climate health initiatives.

Problem Statement

India bears 26% of the global TB burden, yet traditional symptom-based screening fails to detect a large proportion of cases. Limited availability of radiologists, poor care-seeking behaviour, and reliance on manual workflows constrained the effectiveness of community-based Active Case Finding, resulting in missed diagnoses and delayed treatment.

Solution

WJCF deployed an AI-enabled Express Health Camp model using ultraportable chest X-ray devices integrated with an offline-first Radiological Information System (RIS). The system enabled instant AI-driven interpretation, beneficiary data capture, and triage at the point of screening without reliance on internet connectivity allowing large-scale, efficient TB detection in low-resource settings.

Quick Facts

  • The William J. Clinton Foundation (WJCF)
    Organisation Name
    The William J. Clinton Foundation (WJCF)
  • Organisation Website
    Organisation Website
    Visit Site
  • Founding Year
    Founding Year
    2007, India
  • 12,12,932 individuals screened
    Number of Beneficiaries served
    12,12,932 individuals screened
  • 33 districts across 11 Indian states
    Geography Served
    33 districts across 11 Indian states
  • Programmatic Impact
    Focus Area
    Programmatic Impact
  • Program Delivery / Beneficiary Services, Technology & Data Management
    Functions Impacted
    Program Delivery / Beneficiary Services, Technology & Data Management
  • Developed In-house + Partners
    Service Provider
    Developed In-house + Partners
  • msingh@wjcf.in
    Contact Email
    msingh@wjcf.in

Full Case Study

Challenge

High TB burden and diagnostic bottlenecks limited the effectiveness of community-based screening.

Key systemic challenges included:
  • High Disease Burden: India accounted for 26% of global TB cases in 2023.
  • Ineffective Symptom Screening: 42.6% of TB confirmations would have been missed without chest X-rays.
  • Severe Human Resource Gaps: Approximately 20,500 radiologists serve a population of 1.4 billion (~15 per million)
  • Poor Care-Seeking Behaviour: 63% of individuals with chest symptoms did not seek care
The Challenages
challenges
solution
Solution

Embedding real-time AI interpretation into frontline screening workflows.

Outcomes & Impact

Transforming TB screening efficiency and detection outcomes at scale.

  • Deployed RIS across 72 machines nationwide
  • Reduced screening time per beneficiary from 8–10 minutes to under 3 minutes
  • Achieved a Number Needed to Screen (NNS) of 127 for one TB confirmation
  • Detected 32% asymptomatic TB cases, often missed by symptom-based approaches
  • Reduced average screening cost to approximately INR 1.5 per beneficiary
Technology Stack
Name of the Tool Where it was used What it enabled Category
Radiological Information System (RIS) Express Health Camps Offline data capture, AI integration, reporting Proprietary
AI CXR Interpretation Models Field screening Instant triage of presumptive TB cases Commercial
Ultraportable CXR Devices Community screening Point-of-care imaging Commercial
Dashboards & Reporting Tools Program management Data-driven decision-making Proprietary
Key Project Learnings
  • Offline-first systems enabled reliable screening in low-connectivity settings, directly increasing coverage
  • AI-led triage reduced dependence on scarce radiologists, accelerating confirmations
  • Integrating AI into routine workflows lowered costs while improving yield.
Potential for Wider Adaption
Sector Adaptability of the Solution
National TB Programs Scalable deployment for Active Case Finding
State Health Departments Integration into routine screening operations
Global Health Programs Replicable model for high-burden, low-resource settings
Additional Details

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